Wednesday, 28 January 2009

Tetramide




Tetramide may be available in the countries listed below.


Ingredient matches for Tetramide



Mianserin

Mianserin hydrochloride (a derivative of Mianserin) is reported as an ingredient of Tetramide in the following countries:


  • Japan

International Drug Name Search

Sunday, 25 January 2009

Ketamav




Ketamav may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Ketamav



Ketamine

Ketamine hydrochloride (a derivative of Ketamine) is reported as an ingredient of Ketamav in the following countries:


  • Australia

International Drug Name Search

Tri-Profen




Tri-Profen may be available in the countries listed below.


Ingredient matches for Tri-Profen



Ibuprofen

Ibuprofen is reported as an ingredient of Tri-Profen in the following countries:


  • Australia

International Drug Name Search

Saturday, 24 January 2009

Metasedin




Metasedin may be available in the countries listed below.


Ingredient matches for Metasedin



Methadone

Methadone hydrochloride (a derivative of Methadone) is reported as an ingredient of Metasedin in the following countries:


  • Spain

International Drug Name Search

Friday, 23 January 2009

Youfenac




Youfenac may be available in the countries listed below.


Ingredient matches for Youfenac



Diclofenac

Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Youfenac in the following countries:


  • Japan

International Drug Name Search

Friday, 16 January 2009

Aminofilin




Aminofilin may be available in the countries listed below.


Ingredient matches for Aminofilin



Aminophylline

Aminophylline is reported as an ingredient of Aminofilin in the following countries:


  • Bosnia & Herzegowina

  • Serbia

International Drug Name Search

Tuesday, 13 January 2009

Articaine




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

N01BB08

CAS registry number (Chemical Abstracts Service)

0023964-58-1

Chemical Formula

C13-H20-N2-O3-S

Molecular Weight

284

Therapeutic Category

Anesthetic, local

Chemical Name

2-Thiophenecarboxylic acid, 4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-, methyl ester

Foreign Names

  • Articainum (Latin)
  • Articain (German)
  • Articaïne (French)
  • Articaina (Spanish)

Generic Names

  • Articaine (OS: BAN)
  • Articaïne (OS: DCF)
  • Carticaine (OS: BAN)
  • Hoe 045 (IS: Hoechst)
  • Hoe 40045 (IS)
  • Articaine Hydrochloride (OS: BANM, USAN)
  • Carticaine Hydrochloride (IS)
  • Articaine Hydrochloride (PH: Ph. Eur. 6, BP 2010)
  • Articaini hydrochloridum (PH: Ph. Eur. 6)

Brand Names

  • Articaina Epinefrina Diasa (Articaine and Epinephrine)
    Diasa, Spain


  • Ultracain Epinefrina (Articaine and Epinephrine)
    Normon, Spain


  • Alfacaina (Articaine and Epinephrine)
    Dentsply, Italy


  • Alphacaïne (Articaine and Epinephrine)
    Dentsply, France; Heck Pharma, Switzerland


  • Articadent (Articaine and Epinephrine)
    Dentsply, France


  • Articaina con Adrenalina (Articaine and Epinephrine)
    Pierrel, Italy


  • Articaine hydrochloride with Epinephrine] (Articaine and Epinephrine)
    Pierrel, United States


  • Artinibsa (Articaine and Epinephrine)
    Inibsa, Spain


  • Bucanest Adrenalinée (Articaine and Epinephrine)
    Biodica, France


  • Bucanest Sans Vasoconstricteur
    Biodica, France


  • Bucanest (Articaine and Epinephrine)
    Biodica, Australia


  • Cartidont (Articaine and Epinephrine)
    Curaden, Italy


  • Citocartin (Articaine and Epinephrine)
    Molteni, Italy; Molteni, Poland


  • Cystocain
    Jugoremedija, Serbia


  • Déltazine Adrénalinée (Articaine and Epinephrine)
    A.T.O. Zizine, France


  • Déltazine
    A.T.O. Zizine, France


  • Deltazine (Articaine and Epinephrine)
    Ato Zizine, Australia


  • Meganest (Articaine and Epinephrine)
    Clarben, Spain


  • Rudocain (Articaine and Epinephrine)
    Streuli Pharma, Switzerland


  • Septanest (Articaine and Epinephrin)
    Septodont, Austria; Septodont, Bulgaria; Septodont, Denmark; Septodont, Netherlands; Specialites Septodont, Australia; Wild, Switzerland


  • Septanest z adrenalin (Articaine and Adrenalin)
    Septodont, Poland


  • Septocaine
    Septodont, United States


  • Septocaine (Articaine and Epinephrine)
    Deproco, United States; Septodont, Denmark; Septodont, Norway


  • Sopira Citocartin mit Epinephrin (Articaine and Epinephrine)
    Heraeus Medical, Germany


  • Supracaine (Articaine and Epinephrine)
    Richter Gedeon RT, Slovakia


  • Ubistesin (Articaine and Epinephrine)
    3M, Austria; 3M, Switzerland; 3M, New Zealand; 3M ESPE, Germany; 3M ESPE, Poland; 3M ESPE AG, Denmark; 3M Svenska, Sweden; ESPE, Slovenia


  • Ultracain
    Sanofi-Aventis, Germany; Sanofi-Aventis, Georgia; Sanofi-Aventis, Turkey


  • Ultracain (Articaine and Epinephrine)
    Sanofi-Aventis, Austria


  • Ultracain D-S (Articaine and Epinephrine)
    Sanofi-Aventis, Switzerland; Sanofi-Aventis, Germany; Sanofi-Aventis, Netherlands; Sanofi-Aventis, Slovenia


  • Ultracain Suprarenin (Articaine and Epinephrine)
    Sanofi-Aventis, Germany

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Flunifen




Flunifen may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Flunifen



Flunixin

Flunixin meglumine (a derivative of Flunixin) is reported as an ingredient of Flunifen in the following countries:


  • Italy

International Drug Name Search

Sunday, 11 January 2009

botulinum toxin type B


Generic Name: rimabotulinumtoxinB (Myobloc) (RYE ma BOT ue LYE num TOX in B)

Brand Names: Myobloc


What is rimabotulinumtoxinB (Myobloc)?

RimabotulinumtoxinB (Myobloc), also called botulinum toxin type B, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.


Myobloc is used to treat cervical dystonia (severe spasms in the neck muscles).


Myobloc may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Myobloc?


The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.


Call your doctor at once if you have drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur up to several weeks after a botulinum toxin injection. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using this medication more often than prescribed will not make it more effective and may result in serious side effects.


You should not receive this medication if you are allergic to botulinum toxin, or if you have a skin infection in the area where the medicine will be injected.

Before receiving a botulinum toxin injection, tell your doctor if you have ALS ( Lou Gehrig's disease), myasthenia gravis, or Lambert-Eaton syndrome.


The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.


What should I discuss with my healthcare provider before I receive Myobloc?


You should not receive this medication if you are allergic to botulinum toxin, or if you have a skin infection in the area where the medicine will be injected. Tell your doctor if you have ever had a side effect after receiving botulinum toxin in the past.

If you have any of these other conditions, you may need a dose adjustment or special tests:



  • amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");




  • myasthenia gravis;




  • Lambert-Eaton syndrome;




  • a breathing problem such as asthma or emphysema;




  • problems with swallowing;




  • bleeding problems;




  • if you are planning to have surgery; or




  • if you have ever received other botulinum toxin injections such as Botox or Dysport (especially in the last 4 months).



Myobloc is made using human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.


FDA pregnancy category C. It is not know whether botulinum toxin is harmful to an unborn baby. Before you receive this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether botulinum toxin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is Myobloc given?


This medication is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Myobloc injections should be spaced at least 3 months apart.


Your injection may be given into more than one area at a time, depending on the condition being treated.


The effects of a botulinum toxin injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using this medication more often than prescribed will not make it more effective and may result in serious side effects.


What happens if I miss a dose?


Since botulinum toxin has a temporary effect and is given at widely spaced intervals, missing a dose is not likely to be harmful.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, and weak or shallow breathing.


What should I avoid after receiving Myobloc?


Myobloc may impair your vision or depth perception. Be careful if you drive or do anything that requires you to be able to see clearly.

Myobloc side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulism toxin injections, even for cosmetic purposes.


Call your doctor at once if you have any of these serious side effects, some of which can occur up to several weeks after an injection:

  • trouble breathing, talking, or swallowing;




  • hoarse voice, drooping eyelids;




  • unusual or severe muscle weakness (especially in a body area that was not injected with the medication);




  • loss of bladder control;




  • problems with vision; or




  • chest pain.



Less serious side effects may include:



  • pain or muscle weakness near where the medicine was injected;




  • headache, joint or back pain;




  • dry mouth, nausea, upset stomach;




  • fever, cough, sore throat, flu symptoms;




  • pain or stiffness in your neck; or




  • dizziness, drowsiness, anxiety.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Botulinum toxin type B Dosing Information


Usual Adult Dose for Cervical Dystonia:

Initial: The dose should be individualized based on the patient's head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history.

Patients with a prior history of tolerating botulinum toxin injections: 2500 to 5000 units (0.5 to 1.0 mL) divided among affected muscles.

Patients with no history of botulinum toxin type B: use should be at a lower dose, with subsequent dosing based on individual response.

Clinical improvement generally begins within the first two weeks after injection with studies showing the duration of effect to be between 12 and 16 weeks at doses of 5000 units or 10,000 units.

Usual Adult Dose for Hyperhidrosis:

One method being used:
Initial: 2880 units per axilla intradermally for a total dose of 5760 units.

Dilute 5000 unit vial with 1.0 mL of saline in the vial. This dilution technique, when performed in the vial, yields 288 units per 0.1 mL of solution due to the slight overfill in the vial. With this dilution, inject 20 injections of 0.05 mL per axilla may be administered (with an approximate depth of 2 to 3 millimeters), resulting in a total dose of 2880 units per axilla. Injections should be scattered approximately every 2 square centimeters. If injection sites are marked in ink do not inject directly through the ink mark (to avoid a permanent tattoo mark).

Usual Adult Dose for Glabellar Lines:

For glabellar lines and other facial wrinkles: 0.1 mL (500 units) intradermally.

Usual Pediatric Dose for Cervical Dystonia:

The safety and efficacy of botulinum toxin type B for treatment of strabismus in children less than 12 years have not been established.

Initial: The dosage of botulinum toxin type B for the treatment of cervical dystonia should be individualized based on the patient's head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history.

Patients with a prior history of tolerating botulinum toxin injections: 2500 to 5000 units (0.5 to 1.0 mL) intramuscularly divided among affected muscles.

Patients with no history of botulinum toxin type B: use should be at a lower dose, with subsequent dosing based on individual response.

Clinical improvement generally begins within the first two weeks after injection with studies showing the duration of effect to be between 12 and 16 weeks at doses of 5000 units or 10,000 units.

Usual Pediatric Dose for Hyperhidrosis:

One method being used:
Initial: 2880 units per axilla intradermally for a total dose of 5760 units.

Dilute 5000 unit vial with 1.0 mL of saline in the vial. This dilution technique, when performed in the vial, yields 288 units per 0.1 mL of solution due to the slight overfill in the vial. With this dilution, inject 20 injections of 0.05 mL per axilla may be administered (with an approximate depth of 2 to 3 millimeters), resulting in a total dose of 2880 units per axilla. Injections should be scattered approximately every 2 square centimeters. If injection sites are marked in ink do not inject directly through the ink mark (to avoid a permanent tattoo mark).

Usual Pediatric Dose for Glabellar Lines:

The safety and efficacy of botulinum toxin type B for treatment of strabismus in children less than 12 years have not been established.

For glabellar lines and other facial wrinkles: 0.1 mL (500 units) intradermally.


What other drugs will affect botulinum toxin type B?


Other drugs such as cold or allergy medicines, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medications, and irritable bowel medications can increase some of the side effects of Myobloc. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all other medicines you use, especially:



  • an antibiotic such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), neomycin (Mycifradin, Neo-Fradin, Neo-Tab), paromomycin (Humatin, Paromycin), streptomycin, tobramycin (Nebcin, Tobi).



This list is not complete and other drugs may interact with Myobloc. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More botulinum toxin type B resources


  • Botulinum toxin type B Side Effects (in more detail)
  • Botulinum toxin type B Dosage
  • Botulinum toxin type B Use in Pregnancy & Breastfeeding
  • Botulinum toxin type B Drug Interactions
  • Botulinum toxin type B Support Group
  • 0 Reviews for Botulinum toxin type B - Add your own review/rating


Compare botulinum toxin type B with other medications


  • Cervical Dystonia
  • Dystonia
  • Facial Wrinkles
  • Hyperhidrosis


Where can I get more information?


  • Your doctor or pharmacist can provide more information about Myobloc (rimabotulinumtoxinB).

See also: botulinum toxin type B side effects (in more detail)


Friday, 9 January 2009

diclofenac ophthalmic



Generic Name: diclofenac ophthalmic (dye KLOE fen ak off THAL mik)

Brand Names: Voltaren Ophthalmic


What is diclofenac ophthalmic?

Diclofenac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Diclofenac works by reducing hormones that cause inflammation and pain in the body.


Diclofenac ophthalmic (for the eye) is used to reduce swelling, pain, and light sensitivity after cataract surgery or corneal refractive surgery.

Diclofenac ophthalmic may also be used for purposes not listed in this medication guide.


What is the most important information I should know about diclofenac ophthalmic?


You should not use this medication if you are allergic to diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze) or other NSAIDs.

Before using diclofenac ophthalmic, tell your doctor if you are allergic to any medications, or if you have a bleeding or blood-clotting disorder, diabetes, arthritis, glaucoma, dry eye syndrome, or if you have had other recent eye surgeries.


Tell your doctor about all other medications you use, especially a blood thinner such as warfarin (Coumadin, Jantoven).


Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Using the medication for longer than prescribed may increase the risk of serious side effects on your eyes.


For at least 3 days after your surgery, do not wear any contact lens that has not been approved by your doctor. Do not use any other eye medications unless your doctor has prescribed them.

What should I discuss with my healthcare provider before I use diclofenac ophthalmic?


You should not use this medication if you are allergic to diclofenac or other NSAIDs.

To make sure you can safely use diclofenac ophthalmic, tell your doctor if you have any of these other conditions:



  • a bleeding or blood-clotting disorder;




  • diabetes;




  • arthritis;




  • glaucoma;




  • dry eye syndrome; or




  • if you have had other recent eye surgeries.




FDA pregnancy category C. It is not known whether diclofenac ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether diclofenac ophthalmic passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using diclofenac ophthalmic.

How should I use diclofenac ophthalmic?


Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Diclofenac ophthalmic is usually given 24 hours before cataract surgery, and continued for 3 to 14 days after surgery. Using the medication for longer than prescribed may increase the risk of serious side effects on your eyes.


Wash your hands before using eye medication.

To apply the eye drops:



  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.




  • Use the eye drops only in the eye you are having surgery on.




  • Use only the number of drops your doctor has prescribed.




  • Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.




Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.


Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?


Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using diclofenac ophthalmic?


For at least 3 days after your surgery, do not wear any contact lens that has not been approved by your doctor.

Do not use other eye medications during treatment with diclofenac ophthalmic unless your doctor tells you to.


Diclofenac ophthalmic side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • severe burning, stinging, or itching of your eyes;




  • eye pain, redness, or excessive watering;




  • vision changes, increased sensitivity to light;




  • white patches on your eyes;




  • crusting or drainage of your eyes; or




  • dizziness, stomach pain, vomiting, weakness, fever, chills, or flu symptoms (can occur if the medicine is absorbed into your bloodstream).



Less serious side effects may include:



  • mild burning, stinging, or itching of your eyes;




  • swollen or puffy eyelids;




  • nausea, vomiting, stomach pain;




  • weakness, fever or chills;




  • headache;




  • sleep problems (insomnia); or




  • runny nose.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Diclofenac ophthalmic Dosing Information


Usual Adult Dose for Postoperative Ocular Inflammation:

1 drop to the affected eye(s) 4 times a day beginning 24 hours after cataract surgery and continuing throughout the first 2 weeks of the postoperative period. In some patients, treatment has been continued for 6 weeks or longer.

Usual Adult Dose for Inhibition of Intraoperative Miosis:

1 to 2 drops to the affected eye(s) 4 times a day for 3 days prior to surgery. 1 to 2 drops to the affected eye(s) every 15 minutes for 4 doses 1 hour before surgery.
1 drop to the affected eye(s) 15 minutes after surgery and continued 4 times daily starting 4 to 6 hours after surgery for 3 days as needed.

Usual Adult Dose for Corneal Ulcers:

1 drop to the affected eye(s) 4 to 5 times a day.

Usual Adult Dose for Keratoconjunctivitis:

1 drop to the affected eye(s) 4 to 5 times a day.

Usual Adult Dose for Conjunctivitis:

1 drop to the affected eye(s) 4 to 5 times a day.


What other drugs will affect diclofenac ophthalmic?


Tell your doctor about all other medications you use, especially a blood thinner such as warfarin (Coumadin, Jantoven).


There may be other drugs that can interact with diclofenac ophthalmic. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More diclofenac ophthalmic resources


  • Diclofenac ophthalmic Dosage
  • Diclofenac ophthalmic Use in Pregnancy & Breastfeeding
  • Diclofenac ophthalmic Drug Interactions
  • Diclofenac ophthalmic Support Group
  • 0 Reviews for Diclofenac - Add your own review/rating


  • Voltaren Ophthalmic Prescribing Information (FDA)



Compare diclofenac ophthalmic with other medications


  • Conjunctivitis
  • Corneal Ulcer
  • Inhibition of Intraoperative Miosis
  • Keratoconjunctivitis
  • Postoperative Ocular Inflammation


Where can I get more information?


  • Your doctor or pharmacist can provide more information about diclofenac ophthalmic.


Thursday, 1 January 2009

Tofen




Tofen may be available in the countries listed below.


Ingredient matches for Tofen



Ketotifen

Ketotifen fumarate (a derivative of Ketotifen) is reported as an ingredient of Tofen in the following countries:


  • Bangladesh

International Drug Name Search